Corneal thickness evaluation in healthy eyes: Comparison between two different Scheimpflug devices

PLoS One. 2020 Dec 3;15(12):e0243370. doi: 10.1371/journal.pone.0243370. eCollection 2020.

Abstract

Purpose: To evaluate the correlation between corneal thickness (CT) measurements obtained with two Scheimpflug devices, Pentacam HR and Precisio, and to elaborate, if necessary, a regression formula which could make these results comparable.

Design: Retrospective, Comparative, Observational study.

Setting: Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana" University of Salerno, Italy.

Methods: One hundred twenty four healthy eyes of 124 volunteers (65 males; range: 20-32 years; mean age of 24.8 ± 1.7) were included in this study. CT was measured using Pentacam HR and Precisio in three different points: the pupil center (PC), the corneal apex (CA) and the thinnest point (TP).

Results: CT obtained with both devices at the PC, at the CA and at the TP showed a good correlation (r = 0.97, r = 0.97, r = 0.97, respectively), but Pentacam HR measurements were significantly thicker than those provided by Precisio (p < 0.01). The differences between Pentacam HR and Precisio were 21.9 ± 8.8 μm at the PC, 21.9 ± 8.9 μm at the CA, 19.1 ± 9.0 μm at the TP. The calculated regression formulas were: y = 0.9558x + 2.3196 for the PC, y = 0.9519x + 4.5626 for the CA, y = 0.9364x + 15.436 for the TP, where x is the CT measured with Pentacam HR and y is the Precisio measurement.

Conclusions: The findings provided by this study highlight that Precisio measures thinner corneas compared to Pentacam HR. The identified regression formulas could be utilized to make interchangeable the results obtained with these two devices.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Adult
  • Cornea / anatomy & histology
  • Cornea / diagnostic imaging*
  • Corneal Pachymetry / instrumentation*
  • Female
  • Healthy Volunteers
  • Humans
  • Italy
  • Male
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography / instrumentation*
  • Young Adult

Grants and funding

The author(s) received no specific funding for this work.