The Development of Hyaluronic Acids Used for Skin Tissue Regeneration

Curr Drug Deliv. 2021;18(7):836-846. doi: 10.2174/1567201817666201202094513.

Abstract

Burns, mechanical injuries, skin defects, poor wound healing and scars caused by chronic diseases are serious clinical issues that affect millions of people around the world. Hyaluronic acid (HA) is one of the main components of extracellular matrix, which is widely distributed in human body. Because of its unique physical and chemical properties and diversity of physiological functions, hyaluronic acid is widely used in tissue engineering and regenerative medicine. This paper reviews the application of HA and HA based scaffolds in the regeneration and repair of skin tissue, as well as the application of HA in the fields of skin filler, wound healing, beauty, etc.

Keywords: Hyaluronic acid; dermal fillers; hydrogels; scaffold; skin tissue engineering; wound healing..

Publication types

  • Review

MeSH terms

  • Humans
  • Hyaluronic Acid*
  • Hydrogels
  • Skin
  • Tissue Engineering
  • Tissue Scaffolds
  • Wound Healing*

Substances

  • Hydrogels
  • Hyaluronic Acid