Selective Immunoglobulin A Deficiency, Helicobacter pylori Infection, and Strongyloidiasis in a Patient with Adenocarcinoma of the Stomach

Bassel Mazen Dakkak; Yahia Imam; Khalid Ahmed; Ahmed Osman Saleh; Dina Soliman; Meshaal Alanzi; Mohamed A Yassin; Shehab Mohamed

doi:10.1159/000511066

Selective Immunoglobulin A Deficiency, Helicobacter pylori Infection, and Strongyloidiasis in a Patient with Adenocarcinoma of the Stomach

Case Rep Oncol. 2020 Oct 27;13(3):1325-1329. doi: 10.1159/000511066. eCollection 2020 Sep-Dec.

Authors

Bassel Mazen Dakkak¹, Yahia Imam², Khalid Ahmed³, Ahmed Osman Saleh⁴, Dina Soliman³, Meshaal Alanzi¹, Mohamed A Yassin³, Shehab Mohamed³

Affiliations

¹ Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
² Department of Neurology, Weill Cornell Medical College, Doha, Qatar.
³ Department of Hematology, National Centre for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar.
⁴ Department of Endocrinology, Hamad Medical Corporation, Doha, Qatar.

Abstract

Selective immunoglobulin A (IgA) deficiency is one of many congenital immunodeficiencies. It is associated with several medical condition. It has been shown to be associated with some types of malignancies, some autoimmune disorders, and even with some infections. Here we report a young male with selective IgA deficiency who also tested positive for Helicobacter pylori and strongyloidiasis at the time when he was diagnosed with stomach adenocarcinoma. The presence of IgA deficiency with multiple etiological possibilities such as infections and cancer makes this case unusual.

Keywords: Adenocarcinoma; Helicobacter pylori; IgA; Stomach; Strongyloidiasis.

Publication types

Case Reports