This article investigates the problem of fixed-time event-triggered output consensus tracking for high-order multiagent systems (MASs) under directed interaction graphs. First, a fixed-time event-triggered distributed observer and triggering functions are proposed. Next, fixed-time convergence of the presented distributed observer is proved by the Lyapunov function approach, and an analysis is conducted to show the proposed distributed observer excludes zeno behavior. Then, an event-triggered adaptive dynamic surface fixed-time controller is designed to stabilize the tracking error system. Finally, simulation results are given to show the effectiveness and superiority of the consensus scheme developed. The contribution of this article is to present a novel event-triggered fixed-time distributed observer and a novel fixed-time controller, which can reduce frequency of communication and control update, avoid continuous monitor, exclude zeno behavior, eliminate the effect of mismatched disturbance caused by observation error, and achieve practical fixed-time output consensus tracking of high-order MAS under directed interaction graphs.