Functional Magnetic Resonance Imaging-Guided Personalization of Transcranial Magnetic Stimulation Treatment for Depression

Robin F H Cash; Luca Cocchi; Jinglei Lv; Paul B Fitzgerald; Andrew Zalesky

doi:10.1001/jamapsychiatry.2020.3794

Functional Magnetic Resonance Imaging-Guided Personalization of Transcranial Magnetic Stimulation Treatment for Depression

JAMA Psychiatry. 2021 Mar 1;78(3):337-339. doi: 10.1001/jamapsychiatry.2020.3794.

Authors

Robin F H Cash^{1

2}, Luca Cocchi¹, Jinglei Lv^{2

3

4}, Paul B Fitzgerald⁵, Andrew Zalesky^{2

3}

Affiliations

¹ Clinical Brain Networks Team, QIMR Berghofer, Brisbane, Queensland, Australia.
² Melbourne Neuropsychiatry Centre, The University of Melbourne, Victoria, Australia.
³ Department of Biomedical Engineering, The University of Melbourne, Victoria, Australia.
⁴ School of Biomedical Engineering, The University of Sydney, Camperdown, New South Wales, Australia.
⁵ Epworth Centre for Innovation and Mental Health, Epworth Healthcare and the Monash University Central Clinical School, Camberwell, Victoria, Australia.

Abstract

This study assesses whether treatment response for depression could be improved via a single one-site-fits-all dorsolateral prefrontal cortex target, representing the group average optimal site of subgenual cingulate cortex functional connectivity, or whether target site personalization is necessary.

Publication types

Clinical Trial
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Brain Mapping*
Depressive Disorder, Major / diagnostic imaging*
Depressive Disorder, Major / therapy*
Dorsolateral Prefrontal Cortex*
Female
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Outcome and Process Assessment, Health Care
Transcranial Magnetic Stimulation / methods
Transcranial Magnetic Stimulation / standards*

Associated data

ANZCTR/ACTRN12610001071011