Pure erythroid leukemia

Jason C Chen; Winston Y Lee; Jordan K Schaefer; Dale L Bixby

doi:10.1002/ccr3.3056

Pure erythroid leukemia

Clin Case Rep. 2020 Sep 18;8(11):2286-2288. doi: 10.1002/ccr3.3056. eCollection 2020 Nov.

Authors

Jason C Chen¹, Winston Y Lee², Jordan K Schaefer¹, Dale L Bixby¹

Affiliations

¹ Division of Hematology and Medical Oncology Department of Internal Medicine University of Michigan Ann Arbor Michigan.
² Department of Pathology University of Michigan Ann Arbor Michigan.

Abstract

The diagnosis of pure erythroid leukemia (PEL) can be challenging. Prompt identification of CD45+, CD34-, CD71+, CD117+, and E-cadherin+ erythroblasts is important. The differential diagnosis is broad and includes megaloblastic anemia.

Keywords: complex karyotype; erythroblast; erythroid leukemia; myeloid leukemia; tp53 mutation.