Purpose: To examine a possible case of Paget's disease of bone (PDB) in an Indigenous pre-contact male from Canada, individual D of the Skinner site in Ontario.
Methods: Radiographs, CT scan and histological analysis.
Results: The histological analysis revealed the mosaic pattern that characterizes PDB. CT scans show advanced sclerosis of the cranium and a diminished diplӧe with osteolytic lesions.
Conclusions: The pathological features that have been identified are collectively characteristic of PDB.
Significance: The Skinner case advances our understanding of the global history and distribution of PDB.
Limitations of study: Only two New World cases have been identified and neither has been studied in sufficient detail.
Suggestions for future research: The older individuals in precolonial New World skeletal series should be given CT scans, which are non-intrusive, to be followed by histological and genetic analyses when indicated.
Keywords: Canada; Late Woodland; metabolic bone disorder; osteosclerosis; paleopathology.
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