Electrochemical Determination of Nicotine in Tobacco Products Based on Biosynthesized Gold Nanoparticles

Yanqiu Jing; Shanghui Ning; Yu Guan; Mingfeng Cao; Junju Li; Li Zhu; Qili Zhang; Chuance Cheng; Yong Deng

doi:10.3389/fchem.2020.593070

Electrochemical Determination of Nicotine in Tobacco Products Based on Biosynthesized Gold Nanoparticles

Front Chem. 2020 Oct 20:8:593070. doi: 10.3389/fchem.2020.593070. eCollection 2020.

Authors

Yanqiu Jing¹, Shanghui Ning², Yu Guan³, Mingfeng Cao², Junju Li³, Li Zhu², Qili Zhang³, Chuance Cheng¹, Yong Deng²

Affiliations

¹ College of Tobacco Science, Henan Agricultural University, Zhengzhou, China.
² Changde Branch of Hunan Tobacco Corporation, Changde, China.
³ Sichuan of China National Tobacco Corporation, Chengdu, China.

Abstract

In this work, gold nanoparticles were biosynthesized via Plectranthus amboinicus leaf extract as the reducing agent. A series of techniques were used for sample analysis. The biosynthesized gold nanoparticles (bAuNPs) are a uniform size with a spherical shape. The FTIR analysis reveals the presence of many oxygen-containing functional groups on the bAuNP surface. The cyclic voltammetry and electrochemical impedance spectroscopic characterizations reveal that while the bAuNPs have a slightly lower conductivity than chemically synthesized AuNPs (cAuNPs). However, the bAuNPs have a superior electrocatalytic performance toward nicotine reduction. After optimization, the bAuNP-modified SPE could detect nicotine linearly from 10 to 2,000 μM with a low detection limit of 2.33 μM. In addition, the bAuNPs/SPE have been successfully used for nicotine-containing-product analysis.

Keywords: Plectranthus amboinicus; biosynthesis; electrochemical sensor; gold nanoparticle; nicotine.