Impact of stress hyperglycemia on myocardial salvage in patients with ST-Elevation myocardial infarction: Cardiac magnetic resonance study

Indian Heart J. 2020 Sep-Oct;72(5):462-465. doi: 10.1016/j.ihj.2020.08.011. Epub 2020 Aug 19.

Abstract

Cardiovascular complications in ST-segment-elevation myocardial infarction survivors remain substantial despite advances in the management of STEMI. We aimed to determine effect of AH on the area at risk (AAR), final infarct size (FIS), and salvage index (SI) in STEMI patients using cardiac magnetic resonance (CMR). 43 successfully reperfused STEMI patients were recruited. CMR was utilized to estimate AAR and FIS, SI was calculated: SI = AAR- FIS/AAR. AH showed significant positive correlations to FIS (r-value = 0.538, P = < 0.001), and AAR (r-value = 0.435, P = 0.002), and a negative correlation with SI (r-value = -0.378, P = 0.006).

Keywords: Cardiac magnetic resonance; Myocardial salvage; Stress hyperglycemia.

MeSH terms

  • Female
  • Follow-Up Studies
  • Glucose / metabolism*
  • Humans
  • Hyperglycemia / blood*
  • Hyperglycemia / etiology
  • Magnetic Resonance Imaging, Cine / methods*
  • Male
  • Middle Aged
  • Myocardium / metabolism
  • Myocardium / pathology*
  • Retrospective Studies
  • ST Elevation Myocardial Infarction / complications
  • ST Elevation Myocardial Infarction / diagnosis*
  • ST Elevation Myocardial Infarction / therapy
  • Salvage Therapy / methods*

Substances

  • Glucose