Repeated Endovascular Thrombectomy in Patients with Acute Ischemic Stroke in a Single Center

J Stroke Cerebrovasc Dis. 2021 Jan;30(1):105457. doi: 10.1016/j.jstrokecerebrovasdis.2020.105457. Epub 2020 Nov 11.

Abstract

Background: Patients with acute ischemic stroke treated with endovascular thrombectomy may be treated with repeat endovascular thrombectomy (rEVT) in case of recurrent large vessel occlusion (LVO). The purpose of this study is to report the frequency, timing, and outcomes of rEVT in a single center.

Materials and methods: We retrospectively reviewed our databases for anterior or posterior circulation rEVT cases. Patient characteristics, procedural data, and functional outcomes (modified Rankin scale at 90 days) were analyzed. Early and late recurrence of stroke was divided at 30 days.

Results: Of 1025 patients treated between January 2011 and January 2020, 23 (2.2%) underwent rEVT. The median time between the first and second procedure was 185 days; 7 (30.4%) patients were re-treated within 30 days. Eleven patients (47.8%) had different occlusion sites between the two procedures. Good clinical outcome of patients with late ipsilateral recurrence was significantly higher than that of patients with late contralateral recurrence (83.3% vs. 16.7, p = 0.027). Overall good functional outcome after the second procedure was 43.5% (10/23). Overall good functional outcome of early and late recurrence groups were similar (57.1% vs. 37.5%, p = 0.650). One patient died due to an underlying cardiac problem.

Conclusion: rEVT can be performed in patients with recurrent stroke of LVO. Ipsilateral recurrence of stroke was associated with good clinical outcome after rEVT.

Keywords: Acute stroke; Endovascular treatment; Recurrent stroke; Thrombectomy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Databases, Factual
  • Endovascular Procedures* / adverse effects
  • Endovascular Procedures* / mortality
  • Female
  • Humans
  • Ischemic Stroke / diagnosis
  • Ischemic Stroke / mortality
  • Ischemic Stroke / physiopathology
  • Ischemic Stroke / therapy*
  • Male
  • Middle Aged
  • Recovery of Function
  • Recurrence
  • Republic of Korea
  • Retreatment
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Thrombectomy* / adverse effects
  • Thrombectomy* / mortality
  • Time Factors
  • Treatment Outcome