Transfer of short-, medium-, and long-chain chlorinated paraffins to eggs of laying hens after dietary exposure

Abstract

Chlorinated paraffins (CPs) are a complex family of contaminants. Lack of exposure data and an understanding of the fate of these chemicals in the environment affect our ability to reliably assess the human health risk associated with CP exposure. The present study focused on the evaluation of CP transfer from feed to eggs of laying hens exposed over 91 days. Laying hens were provided feed spiked with five technical mixtures of short-, medium- or long-chain CPs and featuring low or high chlorine contents, at concentrations of 200 ng/g each. Eggs were collected daily. All mixtures except the LCCPs with high chlorine content transferred into the eggs, with accumulation ratios increasing with the chain length and chlorine content. Concentrations at the steady-state varied between 41 and 1397 ng/g lw depending on the mixture. Additionally, the homologue-dependant transfer resulted in a change of pattern compared to that from the spiked feed.

Keywords: Accumulation ratio; Chlorinated paraffin; Homologue; Kinetics; Persistent organic pollutant; Transfer.