A 48-Year-Old Woman With Chronic Cough, Dyspnea, and Bronchiectasis

Chest. 2020 Nov;158(5):e245-e249. doi: 10.1016/j.chest.2020.06.058.

Abstract

A 48-year-old woman sought a second opinion for dyspnea and chronic productive cough; she was a never smoker. Mild respiratory symptoms persisted since childhood and had progressively worsened over the previous decade. In addition, an unintentional 30-pound weight loss had occurred over several years. Six years previously, a diagnosis of hypersensitivity pneumonitis was made following right upper lobe wedge resection that revealed chronic bronchiolitis with interstitial pneumonia and non-necrotizing granulomatous inflammation. Subsequent use of prednisone elicited mild intermittent improvement. She had used feather pillows in the past without any other significant exposures. There were no reports of sinus or GI symptoms.

Publication types

  • Case Reports

MeSH terms

  • Alveolitis, Extrinsic Allergic / diagnosis*
  • Aminophenols / administration & dosage*
  • Anti-Bacterial Agents / administration & dosage
  • Bronchiectasis / diagnosis
  • Bronchiectasis / etiology
  • Bronchoscopy / methods*
  • Cefazolin / administration & dosage*
  • Chloride Channel Agonists / administration & dosage
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics*
  • Cystic Fibrosis* / diagnosis
  • Cystic Fibrosis* / physiopathology
  • Cystic Fibrosis* / therapy
  • Diagnosis, Differential
  • Female
  • Genetic Testing
  • Humans
  • Late Onset Disorders / diagnosis
  • Late Onset Disorders / physiopathology
  • Late Onset Disorders / therapy
  • Middle Aged
  • Quinolones / administration & dosage*
  • Staphylococcal Infections* / diagnosis
  • Staphylococcal Infections* / drug therapy
  • Staphylococcus aureus / isolation & purification
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Aminophenols
  • Anti-Bacterial Agents
  • Chloride Channel Agonists
  • Quinolones
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • ivacaftor
  • Cefazolin