Aspergillus mediastinitis in a post-operative immunocompetent child

Indian J Med Microbiol. 2020 Jul-Dec;38(3 & 4):492-495. doi: 10.4103/ijmm.IJMM_20_267.

Abstract

Post-operative Aspergillus mediastinitis is regarded to be a devastating infection, usually affecting patients undergoing cardiothoracic surgery with specific predisposing factors characterised by a high mortality and chronic morbidity. Patient outcome after such a complication is extremely poor despite antifungal therapy and surgery. We describe the case of an immunocompetent 2-month-old child with obstructed supracardiac total anomalous pulmonary venous circulation (TAPVC) and severe pulmonary artery hypertension, who underwent TAPVC repair through median sternotomy and developed post-operative mediastinitis due to Aspergillus flavus.

Keywords: Amphotericin; flavus; sternum.

Publication types

  • Case Reports

MeSH terms

  • Aspergillosis / complications*
  • Aspergillosis / therapy
  • Aspergillus flavus / isolation & purification*
  • Fatal Outcome
  • Humans
  • Immunocompetence
  • Infant
  • Male
  • Mediastinitis / microbiology*
  • Pericardium / microbiology
  • Postoperative Complications / microbiology*
  • Postoperative Complications / therapy
  • Pulmonary Arterial Hypertension / surgery
  • Pulmonary Veins / abnormalities