A porous cellulose-based molecular imprinted polymer for specific recognition and enrichment of resveratrol

Jingsong Cao; Chen Shen; Xiqing Wang; Yawei Zhu; Sansan Bao; Xiaodan Wu; Yujie Fu

doi:10.1016/j.carbpol.2020.117026

A porous cellulose-based molecular imprinted polymer for specific recognition and enrichment of resveratrol

Carbohydr Polym. 2021 Jan 1:251:117026. doi: 10.1016/j.carbpol.2020.117026. Epub 2020 Sep 15.

Authors

Jingsong Cao¹, Chen Shen¹, Xiqing Wang¹, Yawei Zhu¹, Sansan Bao¹, Xiaodan Wu¹, Yujie Fu²

Affiliations

¹ Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China; Engineering Research Center of Forest Bio-preparation, Ministry of Education, Northeast Forestry University, Harbin 150040, China; The College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, China.
² Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China; Engineering Research Center of Forest Bio-preparation, Ministry of Education, Northeast Forestry University, Harbin 150040, China; The College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, China. Electronic address: yujie_fu@163.com.

PMID: 33152850
DOI: 10.1016/j.carbpol.2020.117026

Abstract

A novel resveratrol molecularly imprinted polymer (p-CM@MPS@MIP-Res) was prepared on the surface of silanized porous cellulose microspheres (p-CM@MPS) for the first time, and was successfully applied for the efficient enrichment of targeted resveratrol in Polygonum cuspidatum. The adsorption kinetics and adsorption equilibrium of p-CM@MPS@MIP-Res were also studied in detail. Compared with non-molecularly imprinted polymer (p-CM@MPS@NIP), the prepared p-CM@MPS@MIP-Res showed high adsorption capacity for resveratrol, the adsorption capacity of the p-CM@MPS@MIP-Res could reach to 11.56 mg/g. Furthermore, the stability of the p-CM@MPS@MIP-Res was evaluated and the result showed that the p-CM@MPS@MIP-Res could be reused for 5 runs. Finally, the p-CM@MPS@MIP-Res was applied to enrich the resveratrol in Polygonum cuspidatum sample, the content of resveratrol in the extraction solution could be increased greatly from 4.23 % to 23.74 %, indicating the p-CM@MPS@MIP-Res was a promising adsorbent for efficiently separation and enrichment of resveratrol in Polygonum cuspidatum.

Keywords: Molecular imprinted polymer; Porous cellulose microsphere; Resveratrol; Specific recognition; Structural modification.

MeSH terms

Adsorption
Cellulose / chemistry*
Chemical Fractionation
Chromatography, High Pressure Liquid / methods
Fallopia japonica / chemistry
Kinetics
Microspheres*
Molecular Imprinting
Molecularly Imprinted Polymers / chemistry*
Polymers / chemistry
Porosity
Resveratrol / analysis
Resveratrol / isolation & purification*

Substances

Molecularly Imprinted Polymers
Polymers
Cellulose
Resveratrol