Are epidural corticosteroid injections effective for lumbosacral radicular pain? A Cochrane Review summary with commentary

NeuroRehabilitation. 2020;47(4):509-511. doi: 10.3233/NRE-209008.

Abstract

Background: Epidural corticosteroid injection is one of the most common non-surgical procedures for lumbosacral radicular pain.

Objective: To assess efficacy and safety of epidural corticosteroid injections compared with placebo injections in patients with lumbosacral radicular pain.

Methods: A summary and commentary of a Cochrane Review by Oliveira et al.RESULTS:25 studies with a total of 2740 participants were included in the review. Moderate quality evidence pointed out a small effect on leg pain at immediate and short-term follow-up and on disability at short-term and intermediate follow-up. Adverse events were not different between corticosteroid and placebo injections.

Conclusions: Epidural corticosteroid injection is slightly more effective than placebo for leg pain and disability at short-term follow up. Clinicians and patients however should be informed of the small effect size of the treatment.

Keywords: Epidural corticosteroid injections; low back pain; lumbosacral radicular pain; sciatica.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage*
  • Humans
  • Injections, Epidural / methods
  • Low Back Pain / diagnosis
  • Low Back Pain / drug therapy*
  • Lumbosacral Region*
  • Radiculopathy / diagnosis
  • Radiculopathy / drug therapy*
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones