Cancer risk assessment from exposure to trihalomethanes in showers by inhalation

Environ Res. 2021 May:196:110401. doi: 10.1016/j.envres.2020.110401. Epub 2020 Oct 29.

Abstract

In many countries water disinfection for human consumption is still carried out via chlorination which generates by-products such as trihalomethanes (THM). Exposure to THM constitutes a public health risk as such substances are known to be carcinogenic. This study evaluated exposure to THMs by inhalation in showers and assessed the carcinogenic risk for lifetime exposure. The study population involved students at Universidad de los Andes residing in Bogotá, Colombia. The risk assessment was performed stochastically and the exposure parameters were taken as probability distributions. Most variables were measured in relation to the chosen population. The risk was calculated using two different methodologies but no significant variations were obtained. The average risk calculated for men and women was 56 cases in a million (5.6 × 10-5). A sensitivity analysis was carried out where it was found that the parameters that increase risk the most are the concentration of chloroform in the water, exposure time, and the volume of the shower cubicle.

Keywords: Cancer risk assessment; Disinfection byproducts; Exposure by inhalation in showers; THM exposure management; Trihalomethanes.

MeSH terms

  • Colombia
  • Environmental Exposure
  • Female
  • Humans
  • Male
  • Neoplasms*
  • Risk Assessment
  • Trihalomethanes / toxicity
  • Water Pollutants, Chemical* / analysis
  • Water Pollutants, Chemical* / toxicity

Substances

  • Trihalomethanes
  • Water Pollutants, Chemical