Ozone injection therapy for intervertebral disc herniation

Br Med Bull. 2020 Dec 15;136(1):88-106. doi: 10.1093/bmb/ldaa032.

Abstract

Introduction: Lumbar disc herniation (LDH) is a common cause of low back pain (LBP). Recently, in the setting of LBP caused by LDH, a growing interest in ozone therapies has been observed.

Source of data: Recent published literatures.

Areas of agreement: Being low back pain more common in the elderlies, exploring conservative alternatives to the surgical intervention is of especial interest.

Areas of controversy: Efficacy and feasibility of ozone injections for LDH is debated. Several clinical studies showed controversial results, and the true benefit has not yet been clarified.

Growing points: Systematically summarize current evidences, analyze the quantitative available data and investigate the role of percutaneous ozone therapy for LDH.

Areas timely for developing research: Current evidence encourage the use of ozone therapy for LBP from LDH. These conclusions should be interpret in light of the limitations of the present study.

Keywords: intervertebral disc herniation; low back pain; ozone therapy; percutaneous therapy.

MeSH terms

  • Humans
  • Intervertebral Disc Displacement* / drug therapy
  • Intervertebral Disc*
  • Lumbar Vertebrae
  • Ozone* / therapeutic use
  • Treatment Outcome

Substances

  • Ozone