Introduction: Lumbar disc herniation (LDH) is a common cause of low back pain (LBP). Recently, in the setting of LBP caused by LDH, a growing interest in ozone therapies has been observed.
Source of data: Recent published literatures.
Areas of agreement: Being low back pain more common in the elderlies, exploring conservative alternatives to the surgical intervention is of especial interest.
Areas of controversy: Efficacy and feasibility of ozone injections for LDH is debated. Several clinical studies showed controversial results, and the true benefit has not yet been clarified.
Growing points: Systematically summarize current evidences, analyze the quantitative available data and investigate the role of percutaneous ozone therapy for LDH.
Areas timely for developing research: Current evidence encourage the use of ozone therapy for LBP from LDH. These conclusions should be interpret in light of the limitations of the present study.
Keywords: intervertebral disc herniation; low back pain; ozone therapy; percutaneous therapy.
© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.