Functionalized Carbon Nanohorns as Drug Delivery Platforms

Anastasios Stergiou; Nikos Tagmatarchis

doi:10.1007/978-1-0716-0920-0_2

Functionalized Carbon Nanohorns as Drug Delivery Platforms

Methods Mol Biol. 2021:2207:13-24. doi: 10.1007/978-1-0716-0920-0_2.

Authors

Anastasios Stergiou¹, Nikos Tagmatarchis²

Affiliations

¹ National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, Athens, Greece.
² National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, Athens, Greece. tagmatar@eie.gr.

PMID: 33113124
DOI: 10.1007/978-1-0716-0920-0_2

Abstract

Carbon nanohorns (CNHs) resembling a single-layered graphene sheet wrapped in a conical shape can be chemically modified in order to immobilize, carry, and release biologically active molecules. Here, we describe the major routes for the preparation of CNH-based drug delivery platforms, via covalent coupling and encapsulation, proficient to facilitate the design of sophisticated drug nanocarriers.

Keywords: Biomaterials; Carbon nanohorns; Drug delivery; Encapsulation; Functionalization; Hybrids.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drug Carriers* / chemistry
Drug Carriers* / therapeutic use
Graphite / chemistry*
Nanostructures* / chemistry
Nanostructures* / therapeutic use

Substances

Drug Carriers
Graphite