Isolation of lupeol acetate from fruit peels of Artocarpus camansi

Rosnani Nasution; Nurul Muhabbah; Hira Helwati; Muhammad Bahi; Marianne Marianne; Ulil Amna

doi:10.4103/japtr.JAPTR_6_20

Isolation of lupeol acetate from fruit peels of Artocarpus camansi

J Adv Pharm Technol Res. 2020 Jul-Sep;11(3):148-156. doi: 10.4103/japtr.JAPTR_6_20. Epub 2020 Jul 14.

Authors

Rosnani Nasution¹, Nurul Muhabbah¹, Hira Helwati¹, Muhammad Bahi¹, Marianne Marianne², Ulil Amna³

Affiliations

¹ Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia.
² Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.
³ Department of Chemistry, Faculty of Engineering, Universitas Samudra, Langsa, Indonesia.

Abstract

The purpose of this research is to find a lupeol acetate from Artocarpus camansi fruit peel. Ethyl acetate extract of A. camansi fruit peel was obtained by maceration process. After the process of fractionation, it results 3 subfractions (A, B, and C). The subfraction B was rechromatographed and yielded B2₂ pure isolate. Based on data from proton nuclear magnetic resonance, Fourier transform-infrared, and mass spectrometry (MS from gas chromatography-MS), the B2₂ isolate was suspected as lupeol acetate compound (in this study, the presence of lupeol acetate in the A. camansi fruit peel has been reported for the first time).

Keywords: isolation; Artocarpus camansi; Lupeol acetate.