Transcutaneous laryngeal ultrasonography: A promising tool for otolaryngologists during COVID-19

Am J Otolaryngol. 2021 Jan-Feb;42(1):102772. doi: 10.1016/j.amjoto.2020.102772. Epub 2020 Oct 20.

Abstract

Purpose: With the current COVID-19 outbreak, otolaryngologists are most exposed to the risk of infection due to the nature of the specialty.This is why they are required to find safer diagnostic alternatives minimizing aerosol-generating procedures. The aim of this study is to explore the accuracy of transcutaneous laryngeal ultrasonography (TLUSG) in order to assess vocal fold movement.

Materials and methods: We performed blindly both TLUSG and flexible fiberoptic laryngoscopy(FFL) on 38 patients, from March to June 2020. Patients were divided into two groups:the former with normally mobile vocal folds and the latter with unilateral vocal fold paralysis.

Results: On FFL findings, 10/38 patients (26,31%) had unilateral vocal fold paralysis; on TLUSG results, 9/38 patients (23.68%) presented impaired vocal fold motion. In comparison to laryngoscopy, the sensitivity, specificity, positive predictive value and negative predictive value of TLUSG for assessment of vocal fold mobility was 80%, 96.42%, 88.88%, 93.10% respectively. A significant association between the two techniques was found on the Chi-square test: X2 = 19.7722 (p value <0.00001). Cohen's K value showed a substantial agreement: K = 0,79.

Conclusion: Although TLUSG could undoubtedly not replace laringoscopy, it represents a noninvasive and useful diagnostic tool for otolaryngologists especially during covid-19 pandemic.Data collected about its high sensitivity and specificity suggest that TLUSG could be a reliable method to screen vocal fold paralysis without performing aerosol-generating procedures, thus providing clear visualization of laryngeal real-time movements, even in non-compliant or high-risk infection patients. Our results allow us to consider TLUSG as part of the preoperative assessment of vocal folds in patients undergoing thyroidectomy.

Keywords: COVID-19; Flexible fiberoptic laryngoscopy; Otolaryngology; TLUSG; Transcutaneous laryngeal ultrasonography; Vocal fold paralysis.

MeSH terms

  • Aged
  • COVID-19 / epidemiology*
  • Comorbidity
  • Female
  • Humans
  • Laryngeal Diseases / diagnosis*
  • Laryngeal Diseases / epidemiology
  • Larynx / diagnostic imaging*
  • Male
  • Middle Aged
  • Otolaryngologists*
  • Pandemics*
  • Reproducibility of Results
  • SARS-CoV-2
  • Ultrasonography / methods*