Efficacy of systemic minoxidil and tofacitinib combination in treatment-resistant alopecia universalis

J Cosmet Dermatol. 2021 Jun;20(6):1807-1809. doi: 10.1111/jocd.13812. Epub 2020 Nov 9.

Abstract

Alopecia areata (AA) is an autoimmune nonscarring alopecic disorder, which presents with varying amounts of hair loss, ranging from focal patchy loss to entire scalp and body hair loss. Treatment of AA is a challenging issue within dermatology practice. Although many treatment options are present, response to medications remains unsatisfactory, especially in severe and recalcitrant cases. In this study, we present a case of treatment-resistant AU, which was successfully treated by the combination of tofacitinib and oral minoxidil.

Keywords: alopecia areata; alopecia universalis; oral minoxidil; tofacitinib.

Publication types

  • Case Reports

MeSH terms

  • Alopecia / drug therapy
  • Alopecia Areata* / drug therapy
  • Humans
  • Minoxidil* / therapeutic use
  • Piperidines
  • Pyrimidines / therapeutic use
  • Pyrroles / therapeutic use

Substances

  • Piperidines
  • Pyrimidines
  • Pyrroles
  • Minoxidil
  • tofacitinib

Supplementary concepts

  • Alopecia universalis