Mondor's Disease in SARS-CoV-2 Infection: A Case of Superficial Vein Thrombosis in the Era of COVID-19

Eur J Case Rep Intern Med. 2020 Sep 1;7(10):001803. doi: 10.12890/2020_001803. eCollection 2020.

Abstract

SARS-CoV-2 causes blood hypercoagulability and severe inflammation resulting in an increased risk of thrombosis. Consequently, COVID-19 patients with cardiovascular disease seem to be at higher risk of adverse events. Mondor's disease is a rare, generally self-limiting, thrombosis of the penis. The pathogenesis of Mondor's disease is unknown, and it is usually diagnosed through clinical signs and with Doppler ultrasound evaluation. We describe the case of a young man with COVID-19 infection who manifested Mondor's disease.

Learning points: SARS-CoV-2 infection is associated with an inflammatory response leading to a prothrombotic state and subsequent risk of arterial and venous pathology.Superficial vein thrombosis can occur in COVID-19 patients.

Keywords: COVID-19; Mondor’s disease; SARS-CoV-2; vein thrombosis.