Evaluation of the standard procedure for the treatment of periprosthetic joint infections (PJI) in Germany - results of a survey within the EndoCert initiative

BMC Musculoskelet Disord. 2020 Oct 19;21(1):694. doi: 10.1186/s12891-020-03670-y.

Abstract

Background: The periprosthetic joint infection (PJI) is a severe complication in the field of arthroplasty. Despite the rising number of primary joint replacements, no unified therapeutic standard has been established for the treatment of PJI yet.

Methods: A survey on the principles of treatment of PJI in Germany was conducted. A total of 515 EndoProthetikZentren (EPZ) were included, resulting in a response rate of 100%.

Results: For early infections 97.6% of the centers use prosthesis-preserving procedures (DAIR). A one-stage exchange was implemented by less than 50% of the centers. If implemented, this treatment entails a prior selection of patients for a successful treatment. The two-stage exchange is performed in all centers, and most centers proceed with the implantation of a cemented spacer between stages. 75% of the centers proceed with a center-based concept for the treatment of PJI.

Conclusion: The aim of a uniform PJI standard at the centers has not yet been fully achieved. Further improvements within the certification were initiated. The most relevant treatment options in Germany are displayed. The two-stage revision with a cemented spacer is the most widely implemented treatment. This exposition of principles could help for the further development of standardized treatment guidelines and definitions.

Keywords: Certification; Incident reporting; Periprosthetic joint infection; Revision arthroplasty; Surveys; Two-stage revision.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Debridement
  • Germany / epidemiology
  • Humans
  • Prosthesis-Related Infections* / diagnosis
  • Prosthesis-Related Infections* / epidemiology
  • Prosthesis-Related Infections* / therapy
  • Reoperation
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents