Bacteremia caused by Veillonella dispar in an oncological patient

Anaerobe. 2020 Dec:66:102285. doi: 10.1016/j.anaerobe.2020.102285. Epub 2020 Oct 16.

Abstract

Veillonella dispar is a Gram-negative anaerobic coccus involved in only a few human diseases. We report the second case of bacteremia due to this microorganism in an elderly patient. A 72-year-old man with a history of bladder cancer presented with diarrhea, vomiting, and fever for 48 hours. After the diagnosis of septic shock, four sets of blood cultures were taken, and three of them yielded V. dispar. Resistance to metronidazole, penicillin, and piperacillin-tazobactam was documented. Treatment with clindamycin was started, and the patient was discharged after improvement in his general condition.

Keywords: Anaerobes; Gene sequencing; MALDI TOF MS; Veillonella dispar; blood Cultures.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / diagnosis*
  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Comorbidity
  • DNA, Bacterial
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • RNA, Ribosomal, 16S
  • Urinary Bladder Neoplasms
  • Veillonella / classification*
  • Veillonella / drug effects
  • Veillonella / genetics

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • RNA, Ribosomal, 16S

Supplementary concepts

  • Veillonella dispar