Skin permeation and penetration of crisaborole when coapplied with emollients

J Am Acad Dermatol. 2020 Dec;83(6):1801-1803. doi: 10.1016/j.jaad.2020.03.114. Epub 2020 Oct 14.

Authors

Zoe D Draelos¹, William C Ports², Bonnie Vlahos³, Thean Yeoh², Dan Wu-Linhares², Marc B Brown⁴, Jon Lenn⁵, Avinash G Thombre²

Affiliations

¹ Dermatology Consulting Services, High Point, North Carolina. Electronic address: zdraelos@northstate.net.
² Pfizer Inc, Groton, Connecticut.
³ Pfizer Inc, Collegeville, Pennsylvania.
⁴ MedPharm Ltd, Guildford, United Kingdom.
⁵ MedPharm Ltd, Durham, North Carolina.

PMID: 33069458
DOI: 10.1016/j.jaad.2020.03.114

No abstract available

Publication types

Letter

MeSH terms

Boron Compounds / administration & dosage
Boron Compounds / pharmacokinetics*
Bridged Bicyclo Compounds, Heterocyclic / administration & dosage
Bridged Bicyclo Compounds, Heterocyclic / pharmacokinetics*
Dermatitis, Atopic / drug therapy*
Drug Evaluation, Preclinical
Drug Therapy, Combination
Emollients / administration & dosage*
Humans
Permeability
Skin / metabolism*
Skin Cream / administration & dosage*

Substances

Boron Compounds
Bridged Bicyclo Compounds, Heterocyclic
Emollients
crisaborole