The use of copper to help prevent transmission of SARS-coronavirus and influenza viruses. A general review

Diagn Microbiol Infect Dis. 2020 Dec;98(4):115176. doi: 10.1016/j.diagmicrobio.2020.115176. Epub 2020 Aug 15.

Abstract

The SARS-CoV-2 is the causative agent of the COVID-19 disease, a severe acute respiratory syndrome-coronavirus (SARS-CoV). Its main transmission pathway is through large respiratory droplets, as well as direct and indirect contact. Copper in different formats has been used in research and clinical settings to reduce the risk of bacterial and viral contamination. Therefore, this review aims to search for evidence about the biocidal properties of copper over the Coronaviridae family. A literature review was performed using PubMed and Ovid servers without date or language restrictions. The search was carried out on March 7, 2020, using the following search terms: [Copper] Coronavirus OR CoV OR SARS OR MERS OR Influenza. Copper destroys the replication and propagation abilities of SARS-CoV, influenza, and other respiratory viruses, having high potential disinfection in hospitals, communities, and households. Copper can eliminate pathogenic organisms such as coronavirus bacterial strains, influenza virus, HIV, and fungi after a short period of exposure. Copper seems to be an effective and low-cost complementary strategy to help reduce the transmission of several infectious diseases by limiting nosocomial infectious transmission. Copper oxide or nanocompounds may be used as filters, face masks, clothing, and hospital common surfaces to reduce viruses and bacterial incubation.

Keywords: Copper; Coronavirus; Influenza; Nanoparticles; Severe acute respiratory syndrome.

Publication types

  • Review

MeSH terms

  • Betacoronavirus / drug effects
  • COVID-19
  • Copper / pharmacology*
  • Coronavirus Infections / prevention & control*
  • Coronavirus Infections / transmission
  • Disinfectants / pharmacology*
  • Humans
  • Influenza, Human / prevention & control*
  • Influenza, Human / transmission
  • Orthomyxoviridae / drug effects
  • Pandemics / prevention & control*
  • Pneumonia, Viral / prevention & control*
  • Pneumonia, Viral / transmission
  • SARS-CoV-2

Substances

  • Disinfectants
  • Copper
  • cuprous oxide