The Effect of a County Prehospital FAST-ED Initiative on Endovascular Treatment Times

J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105220. doi: 10.1016/j.jstrokecerebrovasdis.2020.105220. Epub 2020 Aug 13.

Abstract

Background: Acute stroke outcomes depend on timely reperfusion. In 3/2017, local EMS agencies implemented a prehospital triage algorithm with hospital bypass and field activation of the neurointerventional team using the Field Assessment Stroke Triage for Emergency Destination (FAST-ED). A score ≥4 bypasses to a comprehensive stroke center (CSC) and a score ≥6 also has the interventional team field activated off-hours.

Aim: We analyzed effects of this initiative on volume, acute stroke transfers, treatment times, and outcomes and determined the tool's ability to predict large vessel occlusion.

Methods: Stroke cases brought to our center by EMS during 3/2016-2/2018 were analyzed, which included one year before and after FAST-ED implementation. Treatment times were compared on- vs. off-hours and to those with field activation.

Results: Of 1153 patients, 761 (67%) were coded as stroke and 235 (20%) underwent reperfusion. Age, sex, race/ethnicity, stroke severity, length of stay, door-to-needle, and 90-d mRS were comparable between periods. Scale compliance was 85%. Concordance rate of ±1 between EMS and calculated score was 53%. Compared to the previous year, door-to-puncture (DTP) improved by 17 min (p < 0.01) overall, 25 min (p < 0.001) off-hours, and 33 min (p < 0.05) with field activation. A cutoff of 4 vs. 6 would have led to 140% increase in field activations but only 36% increase in procedures.

Conclusions: This prehospital initiative led to faster DTP by up to 33 min. The highest impact was off-hours with field activation. Only 1/3 of activations led to endovascular treatment. FAST-ED≥6 appears to be appropriate for field activation.

Keywords: Emergency response; Endovascular therapy; IV alteplase; Stroke; Triage.

Publication types

  • Comparative Study

MeSH terms

  • After-Hours Care
  • Aged
  • Aged, 80 and over
  • Emergency Medical Services*
  • Endovascular Procedures*
  • Female
  • Florida
  • Humans
  • Male
  • Middle Aged
  • Program Evaluation
  • Prospective Studies
  • Retrospective Studies
  • Stroke / diagnosis
  • Stroke / physiopathology
  • Stroke / therapy*
  • Thrombolytic Therapy*
  • Time Factors
  • Time-to-Treatment*
  • Treatment Outcome
  • Triage*