Glycosylation enhances allergenic activity of major bee venom allergen Api m 1 by adding IgE epitopes

J Allergy Clin Immunol. 2021 Apr;147(4):1502-1504.e5. doi: 10.1016/j.jaci.2020.10.002. Epub 2020 Oct 9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allergens / chemistry
  • Allergens / genetics
  • Allergens / immunology*
  • Animals
  • Basophils / immunology
  • Bee Venoms / immunology*
  • Cell Line, Tumor
  • Epitopes / immunology*
  • Glycosylation
  • Humans
  • Immunoglobulin E / immunology*
  • Insect Proteins / chemistry
  • Insect Proteins / genetics
  • Insect Proteins / immunology*
  • Phospholipases A / chemistry
  • Phospholipases A / genetics
  • Phospholipases A / immunology*
  • Proteins / immunology
  • Rats
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / immunology

Substances

  • Allergens
  • Bee Venoms
  • Epitopes
  • Insect Proteins
  • Proteins
  • Recombinant Proteins
  • Immunoglobulin E
  • Phospholipases A
  • Api m 1 allergen, Apis mellifera