Predictive Nomogram for the Necessity of Tracheotomy During Oral and Oropharyngeal Cancer Surgery

Laryngoscope. 2021 May;131(5):E1489-E1495. doi: 10.1002/lary.29121. Epub 2020 Oct 5.

Abstract

Objectives/hypothesis: The individualized risk of airway obstruction after head and neck cancer surgery is unclear, especially oral and oropharyngeal cancer. The study aimed to establish an individualized predictive model for the necessity of temporary tracheotomy in these patients.

Methods: Patients who underwent oral and oropharyngeal cancer surgery from 1999 to 2019 were retrospectively reviewed. A nomogram was developed and validated in patients treated from 1999 to 2009 and 2010 to 2019, respectively.

Results: In total, 1551 patients were included. Oropharyngeal cancer, large tumor, midline crossing, preoperative radiation, mandibulectomy, flap reconstruction, and neck dissection were independent risk factors of postoperative airway obstruction in the training group (n = 707). A nomogram incorporating these factors had a C-index of 0.931 and was validated in the testing group (n = 844) (C-index, 0.918). Good calibration curves were observed in both groups.

Conclusions: The nomogram successfully predicted the individual risk of postoperative airway obstruction for patients with oral and oropharyngeal cancer.

Level of evidence: 4. Laryngoscope, 131:E1489-E1495, 2021.

Keywords: Tracheotomy; nomogram; oral and oropharyngeal cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Airway Obstruction / epidemiology*
  • Airway Obstruction / etiology
  • Airway Obstruction / surgery
  • Female
  • Humans
  • Male
  • Mandibular Osteotomy / adverse effects
  • Middle Aged
  • Mouth Neoplasms / surgery*
  • Neck Dissection / adverse effects
  • Nomograms
  • Oropharyngeal Neoplasms / surgery*
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Postoperative Complications / surgery
  • Retrospective Studies
  • Risk Assessment / statistics & numerical data
  • Risk Factors
  • Surgical Flaps / adverse effects
  • Surgical Flaps / transplantation
  • Tracheotomy / statistics & numerical data*
  • Young Adult