Acne fulminans concomitant with vasculitis-like symptoms mimicking Henoch-Schoenlein purpura

Pediatr Dermatol. 2020 Nov;37(6):1169-1170. doi: 10.1111/pde.14373. Epub 2020 Oct 1.

Abstract

Acne fulminans is a severe form of acne vulgaris accompanied by systemic symptoms. A 17-year-old Chinese boy presented with an outbreak of necrotic lesions on his face eight days after the onset of palpable purpura, arthralgia, fever, abdominal pain, and proteinuria. He was successfully treated with oral prednisolone and isotretinoin. Vasculitis-like symptoms are rarely reported in acne fulminans; therefore, the physician needs to maintain awareness of this uncommon presentation.

Keywords: Henoch-Schonlein purpura; TNF-α; acne fulminans; autoinflammatory disease; interleukin.

Publication types

  • Case Reports

MeSH terms

  • Acne Vulgaris / diagnosis*
  • Acne Vulgaris / drug therapy
  • Adolescent
  • Arthralgia / etiology
  • Fever / etiology
  • Humans
  • IgA Vasculitis / diagnosis
  • Isotretinoin / therapeutic use*
  • Male
  • Prednisolone / therapeutic use
  • Purpura / diagnosis*
  • Purpura / drug therapy
  • Treatment Outcome
  • Vasculitis / diagnosis*
  • Vasculitis / drug therapy

Substances

  • Prednisolone
  • Isotretinoin