Potential Treatment of Breast and Lung Cancer Using Dicoma anomala, an African Medicinal Plant

Molecules. 2020 Sep 27;25(19):4435. doi: 10.3390/molecules25194435.

Abstract

Globally, cancer has been identified as one of the leading causes of death in public health. Its etiology is based on consistent exposure to carcinogenic. Plant-derived anticancer compounds are known to be less toxic to the normal cells and are classified into acetylenic compounds, phenolics, terpenes, and phytosterols. Dicoma anomala is a perennial herb belonging to the family Asteraceae and is widely distributed in Sub-Saharan Africa and used in the treatment of cancer, malaria, fever, diabetes, ulcers, cold, and cough. This review aimed at highlighting the benefits of D. anomala in various therapeutic applications with special reference to the treatment of cancers and the mechanisms through which the plant-derived agents induce cell death.

Keywords: Dicoma; bioactive compounds; cancer; medicinal plants.

Publication types

  • Review

MeSH terms

  • Africa South of the Sahara
  • Asteraceae / chemistry*
  • Breast Neoplasms / drug therapy*
  • Female
  • Humans
  • Lung Neoplasms / drug therapy*
  • Phytotherapy*
  • Plants, Medicinal / chemistry*