Direct Extraction of Lutein from Wet Macroalgae by Liquefied Dimethyl Ether without Any Pretreatment

Hideki Kanda; Wahyudiono; Siti Machmudah; Motonobu Goto

doi:10.1021/acsomega.0c03358

Direct Extraction of Lutein from Wet Macroalgae by Liquefied Dimethyl Ether without Any Pretreatment

ACS Omega. 2020 Sep 11;5(37):24005-24010. doi: 10.1021/acsomega.0c03358. eCollection 2020 Sep 22.

Authors

Hideki Kanda^{1

2

3}, Wahyudiono¹, Siti Machmudah⁴, Motonobu Goto¹

Affiliations

¹ Department of Materials Process Engineering, Nagoya University, Furocho, Chikusa, Nagoya 464-8603, Japan.
² PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.
³ SATREPS, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.
⁴ Department of Chemical Engineering, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia.

Abstract

Extraction of lutein from raw macroalgae Monostroma nitidum was conducted using a simple method employing dimethyl ether (DME) as a solvent. DME extraction enabled omission of conventional drying and cell wall disruption steps, yielding 0.30 mg/g dry lutein from wet M. nitidum. The yield of extracted lutein was higher than that by chloroform-methanol extraction from freeze-dried and cell-disrupted M. nitidum. DME extraction provides a safe, eco-friendly approach that combines high yields of lutein with unheated drying of wet macroalgae in a single step.