CAR T-Cell Cancer Therapy Targeting Surface Cancer/Testis Antigens

Front Immunol. 2020 Sep 2:11:1568. doi: 10.3389/fimmu.2020.01568. eCollection 2020.

Authors

Mie K Jakobsen¹, Morten F Gjerstorff^{1

2

3}

Affiliations

¹ Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark.
² Department of Oncology, Odense University Hospital, Odense, Denmark.
³ Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Odense, Denmark.

No abstract available

Keywords: CAR T cell; DNA methyltransferase inhibitor; T cell engineering; cancer immunotherapy; cancer/testis antigen.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antigens, Neoplasm / immunology
Humans
Immunotherapy, Adoptive* / adverse effects
Immunotherapy, Adoptive* / methods
Neoplasms / diagnosis
Neoplasms / immunology*
Neoplasms / therapy*
T-Lymphocytes / immunology*
T-Lymphocytes / metabolism*
Treatment Outcome

Substances

Antigens, Neoplasm