Graphene Oxide Quantum Dot-Based Functional Nanomaterials for Effective Antimicrobial Applications

Abstract

Conventional β-lactam antibiotics are resisted by bacteria at an increasing rate, prompting studies into the development of alternate antibiotic agents. In this personal account, we summarize recent progress in the design and engineering of graphene oxide quantum dot-based nanomaterials as potent antimicrobial agents. Specifically, we examine the impacts of chemical reduction on the antimicrobial activity of graphene oxide quantum dots, and enhancement of the bactericidal performance by the formation of nanocomposites with metal oxide nanoparticles, within the context of photodynamic generation of reactive oxygen species. A perspective is also included where the promises and challenges are highlighted in the development of high-performance antimicrobial agents based on graphene derivatives.

Keywords: antimicrobial; graphene oxide quantum dot; metal oxide; nanocomposite; photodynamic.