Holmes Tremor

Excerpt

Gordon Holmes reported in 1904 a series of patients with focal brain damage presenting tremors. Holmes tremor can present at rest or with movement (intention), usually with a sustained posture. It is slow (< 4.5 Hz) but with a large amplitude. It has also been referred to as rubral tremor, midbrain tremor, thalamic tremor, post-traumatic tremor, or complex tremor because of the affected areas in the brain. The tremor was mostly associated with lesions in the midbrain, but now many other regions have been recognized.