Impact of the COVID-19 pandemic on the disease course of patients with inflammatory rheumatic diseases: results from the Swiss Clinical Quality Management cohort

Ann Rheum Dis. 2021 Feb;80(2):238-241. doi: 10.1136/annrheumdis-2020-218705. Epub 2020 Sep 22.

Abstract

Objectives: To investigate whether the transient reduction in rheumatology services imposed by virus containment measures during the COVID-19 pandemic was associated with disease worsening in axial spondyloarthritis (axSpA), rheumatoid arthritis (RA) or psoriatic arthritis (PsA).

Methods: Patient-reported disease activity assessed during face-to-face visits and/or via a smartphone application were compared between three periods of each 2 months duration (before, during and after the COVID-19-wave) from January to June 2020 in 666 patients with axSpA, RA and PsA in the Swiss Clinical Quality Management cohort.

Results: The number of consultations dropped by 52%, whereas the number of remote assessments increased by 129%. The proportion of patients with drug non-compliance slightly increased during the pandemic, the difference reaching statistical significance in axSpA (19.9% vs 13.2% before the pandemic, p=0.003). The proportion of patients with disease flares remained stable (<15%). There was no increase in mean values of the Bath Ankylosing Disease Activity Index, the Rheumatoid Arthritis Disease Activity Index-5 and the Patient Global Assessment in patients with axSpA, RA and PsA, respectively.

Conclusion: A short interruption of in-person patient-rheumatologist interactions had no major detrimental impact on the disease course of axSpA, RA and PsA as assessed by patient-reported outcomes.

Keywords: ankylosing; arthritis; epidemiology; psoriatic; rheumatoid; spondylitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Psoriatic / drug therapy
  • Arthritis, Psoriatic / physiopathology*
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / physiopathology*
  • COVID-19*
  • Cohort Studies
  • Disease Progression
  • Female
  • Humans
  • Male
  • Medication Adherence / statistics & numerical data
  • Middle Aged
  • Mobile Applications
  • Patient Reported Outcome Measures
  • Rheumatic Diseases / physiopathology
  • Rheumatology
  • SARS-CoV-2
  • Smartphone
  • Spondylarthropathies / drug therapy
  • Spondylarthropathies / physiopathology*
  • Switzerland
  • Symptom Flare Up*

Substances

  • Antirheumatic Agents