Successfully treated severe COVID-19 and invasive aspergillosis in early hematopoietic cell transplantation setting

Manuela Spadea; Francesca Carraro; Francesco Saglio; Elena Vassallo; Rosanna Pessolano; Massimo Berger; Carlo Scolfaro; Sergio Grassitelli; Franca Fagioli

doi:10.1111/tid.13470

Successfully treated severe COVID-19 and invasive aspergillosis in early hematopoietic cell transplantation setting

Transpl Infect Dis. 2021 Apr;23(2):e13470. doi: 10.1111/tid.13470. Epub 2020 Sep 29.

Authors

Manuela Spadea¹, Francesca Carraro¹, Francesco Saglio¹, Elena Vassallo¹, Rosanna Pessolano¹, Massimo Berger¹, Carlo Scolfaro², Sergio Grassitelli³, Franca Fagioli¹

Affiliations

¹ Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, University of Turin, Turin, Italy.
² Pediatric Infectious Disease Unit, Regina Margherita Children's Hospital, University of Turin, Turin, Italy.
³ Pediatric Intensive Care Unit, Regina Margherita Children's Hospital, Turin, Italy.

No abstract available

Keywords: COVID-19 management; hematopoietic cell transplantation; immune suppressed patients; invasive aspergillosis co-infection; ruxolitinib; severe COVID-19.

Publication types

Case Reports
Letter

MeSH terms

Adenosine Monophosphate / administration & dosage
Adenosine Monophosphate / analogs & derivatives
Alanine / administration & dosage
Alanine / analogs & derivatives
Amphotericin B / administration & dosage
COVID-19 / diagnosis
COVID-19 / immunology
COVID-19 / virology
COVID-19 Drug Treatment*
Coinfection / diagnosis
Coinfection / drug therapy*
Coinfection / immunology
Coinfection / microbiology
Drug Therapy, Combination / methods
Graft vs Host Disease / immunology
Graft vs Host Disease / prevention & control
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Immunosuppressive Agents / administration & dosage
Immunosuppressive Agents / adverse effects*
Invasive Pulmonary Aspergillosis / diagnosis
Invasive Pulmonary Aspergillosis / drug therapy*
Invasive Pulmonary Aspergillosis / immunology
Invasive Pulmonary Aspergillosis / microbiology
Lung / diagnostic imaging
Male
Methylprednisolone / administration & dosage
Myeloablative Agonists / administration & dosage
Myeloablative Agonists / adverse effects
Nitriles
Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
Pyrazoles / administration & dosage
Pyrimidines
SARS-CoV-2 / immunology
SARS-CoV-2 / isolation & purification
Severity of Illness Index
Tomography, X-Ray Computed
Transplantation Conditioning / adverse effects
Transplantation Conditioning / methods
Treatment Outcome
Young Adult

Substances

Immunosuppressive Agents
Myeloablative Agonists
Nitriles
Pyrazoles
Pyrimidines
liposomal amphotericin B
remdesivir
Adenosine Monophosphate
Amphotericin B
ruxolitinib
Alanine
Methylprednisolone