Paraganglioma of the middle mediastinum

Mandeep Singh Rahi; Kulothungan Gunasekaran; Kwesi Amoah; Daniel Rudolph

doi:10.1016/j.rmcr.2020.101211

Paraganglioma of the middle mediastinum

Respir Med Case Rep. 2020 Sep 1:31:101211. doi: 10.1016/j.rmcr.2020.101211. eCollection 2020.

Authors

Mandeep Singh Rahi¹, Kulothungan Gunasekaran¹, Kwesi Amoah¹, Daniel Rudolph¹

Affiliation

¹ Division of Pulmonary Diseases and Critical Care Medicine, Yale-New Haven Health Bridgeport Hospital, Bridgeport, CT, USA.

Abstract

A 60-year-old female was evaluated for significant weight loss, nausea, vomiting, and dysphagia. A computed tomography (CT) of the chest showed a 3 cm mass in the middle mediastinum. CT scan of the abdomen and pelvis revealed no abnormality. Positron emission tomography (PET) of the whole body revealed tracer uptake in the pre-carinal nodal mass. There were no other suspicious foci of tracer uptake. Mediastinoscopy and biopsy revealed a well-differentiated low-grade neuroendocrine tumor. She underwent sternotomy, and after careful mobilization of the great vessels, the middle mediastinal mass was successfully resected. Final pathology revealed a paraganglioma with no morphological signs to suggest malignancy. The right lower paratracheal lymph node did not show any tumor cells. She did well postoperatively.

Keywords: Mediastinum; Neuroendocrine tumor; Paraganglioma.

Publication types

Case Reports