Polyester Vascular Graft Material and Risk for Intracavitary Thoracic Vascular Graft Infection1

Emerg Infect Dis. 2020 Oct;26(10):2448-2452. doi: 10.3201/eid2610.191711.

Abstract

Prosthetic vascular graft infections of the thoracic aorta are rare but can be fatal. Our comparison of collagen- and gelatin-coated grafts showed that collagen-coated grafts were associated with increased biofilm formation and bacterial adherence in vitro and with higher rates of perioperative vascular graft infections in vivo.

Keywords: Prosthetic vascular graft infection; VASGRA; bacteria; biofilm; coating; collagen-coated; gelatin-coated; polyester.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Vessel Prosthesis / adverse effects
  • Collagen
  • Gelatin
  • Humans
  • Polyesters*
  • Prosthesis-Related Infections* / epidemiology

Substances

  • Polyesters
  • Gelatin
  • Collagen