A case of bone marrow involvement in sarcoidosis with crescentic glomerular lesions

Mayu Sugai; Okinori Murata; Hiroki Oikawa; Hiroshi Katagiri; Ami Matsumoto; Hiromi Nagashima; Tamotsu Sugai; Makoto Maemondo

doi:10.1016/j.rmcr.2020.101202

A case of bone marrow involvement in sarcoidosis with crescentic glomerular lesions

Respir Med Case Rep. 2020 Aug 28:31:101202. doi: 10.1016/j.rmcr.2020.101202. eCollection 2020.

Authors

Mayu Sugai¹, Okinori Murata¹, Hiroki Oikawa², Hiroshi Katagiri¹, Ami Matsumoto¹, Hiromi Nagashima¹, Tamotsu Sugai³, Makoto Maemondo¹

Affiliations

¹ Division of Respiratory Medicine, Department of Internal Medicine, Iwate Medical University School of Medicine, Iwate, Japan.
² Department of Pathology, Iwate Medical University School of Medicine, Iwate, Japan.
³ Department of Molecular Diagnostic Pathology, Iwate Medical University School of Medicine, Iwate, Japan.

Abstract

Renal and bone marrow involvements in sarcoidosis are rare. We experienced the case of a 67-year-old man with systemic sarcoidosis, with bone marrow involvement, hepatic involvement and a unique constellation of renal lesion with cellular crescent formation. Immunosuppressive therapy was helpful for maintaining the stability of his pancytopenia, hepatic function and renal function. To the best of our knowledge, the association between sarcoidosis, bone marrow involvement and crescentic glomerulonephritis has been reported in only few cases in literature.

Keywords: Bone marrow involvement; Pancytopenia; Renal sarcoidosis; Sarcoidosis.

Publication types

Case Reports