Abstract
Myrtucyclitones A-C ((+)- and (-)-1-3), three pairs of new triketone-phloroglucinol-triketone hybrids were isolated from the plant Myrtus communis. Their structures with absolute configurations were established by NMR analysis and chemical calculations. Myrtucyclitones B and C exhibited remarkable antibacterial effect.
Keywords:
Myrtus communis; antibacterial effect; triketone-phloroglucinol-triketone adduct.
© 2020 Wiley-VHCA AG, Zurich, Switzerland.
MeSH terms
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Anti-Bacterial Agents / chemistry*
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology
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Circular Dichroism
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Gram-Negative Bacteria / drug effects
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Gram-Positive Bacteria / drug effects
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Ketones / chemistry*
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Molecular Conformation
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Myrtus / chemistry*
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Myrtus / metabolism
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Phloroglucinol / chemistry*
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Plant Leaves / chemistry
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Plant Leaves / metabolism
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Plant Stems / chemistry
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Plant Stems / metabolism
Substances
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Anti-Bacterial Agents
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Ketones
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Phloroglucinol