Objective: To investigate the dietary exposure level of advanced glycation end products(AGEs) in the diet of Shenzhen residents.
Methods: 3 markets, 6 supermarkets and 10 chain catering units in Shenzhen were selected as sampling points. 196 food samples were collected in 11 categories in batches from December 2016 to October 2017. The AGEs content database was obtained by detecting carboxy methyl lysine by ELISA competition method. Combined with the food consumption data of Shenzhen residents in the 2011 survey of dietary and nutritional status of Shenzhen residents, through Monte Carlo simulation, the probability distribution of AGEs dietary exposure was calculated by using the Latin hypercube method from the AGEs content data and consumption data, and the result were expressed by the exposure corresponding to different percentiles(P50 and P95).
Results: In Shenzhen, 50% of the population had a dietary exposure of more than 37. 2 mg/d per person, while 5% of the population had a dietary exposure of more than 65. 9 mg/d per person. The first three factors that had a great impact on the dietary exposure of AGEs were the AGEs content of cereal and its products, the AGEs content of meat and its products, and the consumption of cereal and its products. The top three sources of AGEs exposure for both P50 and P95 were cereal and its products and its products taste, meat and its products.
Conclusion: 5% of Shenzhen residents had a high intake of AGEs, which mainly came from cereals and their products, condiments, meat and their products.
Keywords: advanced glycation end products; carboxy methyl lysine; dietary exposure; probability assessment.