Repair of aortoesophageal fistula with homograft aortic replacement and primary esophageal closure

J Thorac Cardiovasc Surg. 2022 Jun;163(6):2002-2008. doi: 10.1016/j.jtcvs.2020.06.035. Epub 2020 Jun 27.

Abstract

Objectives: The presence of a fistula between the thoracic aorta and the esophagus is a rare and highly fatal condition. This study aimed to evaluate the outcomes of the surgical treatment of an aortoesophageal fistula (AEF).

Methods: We retrospectively reviewed patients with AEF who underwent surgery at our institution.

Results: Between 2007 and 2018, a total of 10 patients who underwent surgery for AEF. The mean age was 63 ± 12 years, and 6 patients were men. Four patients had primary AEFs and 6 patients had secondary AEFs (3 graft replacements and 3 thoracic endovascular aortic repairs). The timing of AEF since graft replacement or thoracic endovascular aortic repairs was 21.6 ± 27 days. We performed aortic replacement with a prosthetic graft (4 patients) or a homograft (5 patients) and extra-anatomical bypass due to a previous aortic graft infection (1 patient). As a treatment of the esophagus, we conducted primary repair in 7 of 10 patients. The median lengths of hospital and intensive care unit stay were 59 days (range, 9-225 days) and 6.3 days (range, 1-87 days), respectively. Seven patients achieved oral feeding after a median 10.3 postoperative days (range, 7-78 postoperative days). Two of the 10 patients died of sepsis at 9 and 74 days postoperatively.

Conclusions: The strategy for patients with AEF should be individualized. Our surgical strategy for AEF, which includes simultaneous aortic graft replacement and primary repair of esophagus in the same operative field, is feasible and promising.

Keywords: TEVAR; aorto-esophageal fistula; homograft; primary repair of esophagus.

MeSH terms

  • Aged
  • Allografts / surgery
  • Aortic Diseases* / diagnostic imaging
  • Aortic Diseases* / etiology
  • Aortic Diseases* / surgery
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Endovascular Procedures* / adverse effects
  • Esophageal Fistula* / diagnostic imaging
  • Esophageal Fistula* / etiology
  • Esophageal Fistula* / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Vascular Fistula* / diagnostic imaging
  • Vascular Fistula* / etiology
  • Vascular Fistula* / surgery