The role of sentinel lymph node mapping in endometrial carcinoma

Minerva Ginecol. 2020 Dec;72(6):367-383. doi: 10.23736/S0026-4784.20.04626-2. Epub 2020 Sep 14.

Abstract

Endometrial cancer is the most commonly diagnosed gynecological malignancy in developing countries, and the second malignancy after cervical cancer in developing countries. The primary treatment is based on surgical and pathologic staging including extrafascial type A radical hysterectomy bilateral salpingo-oophorectomy and pelvic and latero-aortic lymphadenectomy. Minimally invasive surgery is the most widely used technique. Sentinel node biopsy is part of this concept and has reached the management of endometrial cancer. The aim of this review was to describe the history, the different injection techniques and results of sentinel node biopsy, and analyze the future role of this technique in endometrial carcinoma.

Publication types

  • Review

MeSH terms

  • Colorimetry / methods
  • Coloring Agents
  • Endometrial Neoplasms / diagnostic imaging
  • Endometrial Neoplasms / pathology*
  • Endometrial Neoplasms / surgery
  • Female
  • Humans
  • Hysterectomy / methods
  • Indocyanine Green / administration & dosage
  • Injections / methods
  • Lymph Node Excision / methods
  • Methylene Blue
  • Radiopharmaceuticals / administration & dosage
  • Rosaniline Dyes
  • Sentinel Lymph Node / diagnostic imaging
  • Sentinel Lymph Node / pathology*
  • Sentinel Lymph Node Biopsy / methods*
  • Sentinel Lymph Node Biopsy / trends
  • Spectroscopy, Near-Infrared
  • Technetium Tc 99m Aggregated Albumin / administration & dosage

Substances

  • Coloring Agents
  • Radiopharmaceuticals
  • Rosaniline Dyes
  • Technetium Tc 99m Aggregated Albumin
  • iso-sulfan blue
  • sulfan blue
  • Indocyanine Green
  • Methylene Blue