A fully digital workflow for the design and manufacture of prostheses for maxillectomy defects was described. Three-dimensional images from spiral computed tomography and intraoral scanning were used to generate a three-dimensional digital cast of a maxillectomy defect. The obturator prosthesis was then designed on the digital cast by combining dental computer-aided design and reverse engineering software programs. The prosthesis was subsequently milled from polyetheretherketone or three-dimensional-printed from polylactic acid.
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