•Three patients with cytology positive pericardial effusions from high grade serous carcinoma.•Patients' conditions amenable to treatment with chemotherapy after effusion symptom improvement.•Patient with pericardial effusion from high grade serous ovarian cancer post a poly ADP ribose polymerase inhibitor.
Keywords: High grade serous ovarian carcinoma; Pericardial effusion.
© 2020 The Authors.