Coagulation factors induce human skin mast cell and basophil degranulation via activation of complement 5 and the C5a receptor

J Allergy Clin Immunol. 2021 Mar;147(3):1101-1104.e7. doi: 10.1016/j.jaci.2020.08.018. Epub 2020 Sep 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Basophils / immunology*
  • Blood Coagulation Factors / metabolism*
  • Cell Degranulation
  • Cells, Cultured
  • Chronic Urticaria / immunology*
  • Complement C5 / metabolism*
  • Histamine Release
  • Humans
  • Mast Cells / immunology*
  • Receptor, Anaphylatoxin C5a / metabolism*
  • Skin / immunology*

Substances

  • Blood Coagulation Factors
  • Complement C5
  • Receptor, Anaphylatoxin C5a