The European Federation for Medicinal Chemistry (EFMC) Best Practice Initiative: Validating Chemical Probes

ChemMedChem. 2020 Dec 15;15(24):2388-2390. doi: 10.1002/cmdc.202000597. Epub 2020 Sep 3.

Abstract

As part of an initiative aimed to share best practices in Medicinal Chemistry, the European Federation for Medicinal Chemistry (EFMC) is preparing a series of webinars and slide sets focused on the early phase of drug discovery. This educational material is freely accessible through the EFMC. The main target audiences are students or early career scientists and we also believe it will be valuable for experienced practitioners. The first of the series is focused on the generation and validation of high-quality chemical probes, which are critical for drug discovery and more broadly to further our understanding of human biology and disease.

Keywords: Best practices; Chemical probes; Guidelines.

MeSH terms

  • Chemistry, Pharmaceutical / education*
  • Drug Discovery / education*
  • Europe
  • Humans
  • Indicators and Reagents / chemistry
  • Indicators and Reagents / standards*
  • International Agencies*
  • Societies, Scientific*
  • Webcasts as Topic*

Substances

  • Indicators and Reagents