Components and Architecture of the Rhabdovirus Ribonucleoprotein Complex

Christiane Riedel; Alexandru A Hennrich; Karl-Klaus Conzelmann

doi:10.3390/v12090959

Components and Architecture of the Rhabdovirus Ribonucleoprotein Complex

Viruses. 2020 Aug 29;12(9):959. doi: 10.3390/v12090959.

Authors

Christiane Riedel¹, Alexandru A Hennrich², Karl-Klaus Conzelmann²

Affiliations

¹ Institute of Virology, Department of Pathobiology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
² Max von Pettenkofer-Institute Virology, Faculty of Medicine, and Gene Center, LMU Munich, 81377 Munich, Germany.

Abstract

Rhabdoviruses, as single-stranded, negative-sense RNA viruses within the order Mononegavirales, are characterised by bullet-shaped or bacteroid particles that contain a helical ribonucleoprotein complex (RNP). Here, we review the components of the RNP and its higher-order structural assembly.

Keywords: lagos bat virus; lyssavirus; rabies virus; rhabdoviruses; ribonucleoprotein structure; vesicular stomatitis virus; vesiculovirus.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Nucleocapsid Proteins / chemistry
Nucleocapsid Proteins / ultrastructure
Protein Conformation
Rhabdoviridae / chemistry*
Rhabdoviridae / genetics
Ribonucleoproteins / chemistry*
Ribonucleoproteins / ultrastructure
Viral Matrix Proteins / chemistry
Viral Matrix Proteins / ultrastructure
Viral Proteins / chemistry*
Viral Proteins / ultrastructure
Viral Replicase Complex Proteins / chemistry
Viral Replicase Complex Proteins / ultrastructure
Virion / chemistry

Substances

Nucleocapsid Proteins
Ribonucleoproteins
Viral Matrix Proteins
Viral Proteins
Viral Replicase Complex Proteins