Generation of two induced pluripotent stem cell lines IMAGINi004-A and IMAGINi005-A from healthy donors

Eddy Quelennec; Celine Banal; Matthieu Hamlin; Dimartino Clémantine; Marie Michael; Nathalie Lefort

doi:10.1016/j.scr.2020.101959

Generation of two induced pluripotent stem cell lines IMAGINi004-A and IMAGINi005-A from healthy donors

Stem Cell Res. 2020 Oct:48:101959. doi: 10.1016/j.scr.2020.101959. Epub 2020 Aug 20.

Authors

Eddy Quelennec¹, Celine Banal¹, Matthieu Hamlin¹, Dimartino Clémantine¹, Marie Michael¹, Nathalie Lefort²

Affiliations

¹ Université de Paris, Imagine Institute, iPSC Core Facility, INSERM UMR U1163, F-75015 Paris, France.
² Université de Paris, Imagine Institute, iPSC Core Facility, INSERM UMR U1163, F-75015 Paris, France. Electronic address: nathalie.lefort@inserm.fr.

PMID: 32866896
DOI: 10.1016/j.scr.2020.101959

Abstract

Human pluripotent stem cells offer a limitless source of cells for regenerative medicine. They are also highly valuable as tools to study development and pathologies or as cellular substrates to screen and test new drugs. We generated human induced pluripotent stem cell (hiPSC) lines from two unrelated healthy control donors. Peripheral blood mononuclear cells (PBMCs) from these donors were reprogrammed by non-integrative viral transduction, had normal karyotypes and expressed pluripotency hallmarks.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Line
Humans
Induced Pluripotent Stem Cells*
Leukocytes, Mononuclear
Regenerative Medicine